The success of cell culture derived drugs in recent years led to an increasing demand for adequate media components:

Safe: without risk of transmissible spongiform encephalopathy, viral and bacterial contamination,

Cost effective: for replacement of expensive components like foetal calf serum, growth factors,

Highly performing: growth, metabolite production.

Bio Springer has developed special high quality yeast derived nutrients for cell culture media formulation naturally extracted from Saccharomyces cerevisiae selected strains (Springer® UF range).

Bio Springer cell culture nutrients main characteristics:

Balanced sources of easily assimilated amino acids and peptides,

Rich in growth factors like vitamins, minerals, nucleotides, and phosphorus,

Meet the high requirements of biopharmaceutical drugs and vaccines manufacturing,

Safe: Animal-free, allergen free, high microbiological quality,

Low endotoxin level,

High consistency,

Ultrafiltered to guaranty high solubility and filterability.

Bio Springer yeast derived nutrients are recommended as media supplements in order to:

Improve growth viability of industrial cell lines like CHO, hybridomas, VERO, BHK in serum-free and protein free media;

Increase the production of recombinant proteins and monoclonal antibodies;

Reduce quantity of expensive or unsafe ingredients,

Replace mixtures of crystalline amino acids.

Typical concentration in media: 0.1 - 0.8%.

Example: